(<i>E</i>)-(1-(4-Ethoxycarbonylphenyl)-5-(3,4-dimethoxyphenyl)-3-(3,4-dimethoxystyryl)-2-pyrazoline: Synthesis, Characterization, DNA-Interaction, and Evaluation of Activity Against Drug-Resistant Cell Lines

(<i>E</i>)-(1-(4-Ethoxycarbonylphenyl)-5-(3,4-dimethoxyphenyl)-3-(3,4-dimethoxystyryl)-2-pyrazoline: Synthesis, Characterization, DNA-Interaction, and Evaluation of Activity Against Drug-Resistant Cell Lines

(<i>E</i>)-1-(4-Ethoxycarbonylphenyl)-5-(3,4-dimethoxyphenyl)-3-(3,4-dimethoxystyryl)-2-pyrazoline was synthesized via the cyclization reaction between the monocarbonyl curcuminoid (2<i>E</i>,6<i>E</i>)-2,6-bis(3,4-dimethoxybenzylidene)acetone and ethyl hydrazinob...

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Bibliographic Details
Main Authors: Dimitris Matiadis, Barbara Mavroidi, Angeliki Panagiotopoulou, Constantinos Methenitis, Maria Pelecanou, Marina Sagnou
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Molbank
Subjects:
pyrazolines
curcuminoids
nitrogen heterocycles
cytotoxic
dna binding
mdr reversal
Online Access:https://www.mdpi.com/1422-8599/2020/1/M1114

Internet

https://www.mdpi.com/1422-8599/2020/1/M1114

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