From bench to bedside: Calprotectin (S100A8/S100A9) as a biomarker in rheumatoid arthritis

S100A9/S100A8 (calprotectin), a member of the S100 protein family, has been shown to play a pivotal role in innate immunity activation. Calprotectin plays a critical role in the pathogenesis of rheumatoid arthritis (RA), as it triggers chemotaxis, phagocyte migration and modulation of neutrophils an...

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Bibliographic Details
Main Authors: José Inciarte-Mundo, Beatriz Frade-Sosa, Raimon Sanmartí
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1001025/full