Intravenous delivery of enzalutamide based on high drug loading multifunctional graphene oxide nanoparticles for castration-resistant prostate cancer therapy

Intravenous delivery of enzalutamide based on high drug loading multifunctional graphene oxide nanoparticles for castration-resistant prostate cancer therapy

Abstract Background Enzalutamide (Enz) has shown limited bioavailability via oral administration. Castration-resistant prostate cancer (CRPC) is frequent among patients receiving 18–24 months of androgen deprivation therapy. The nonsteroidal anti-androgen enzalutamide (Enz) used in the treatment of...

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Bibliographic Details
Main Authors: Wenjun Jiang, Jiyuan Chen, Chunai Gong, Yuanyuan Wang, Yuan Gao, Yongfang Yuan
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Journal of Nanobiotechnology
Subjects:
Redox-sensitive
Enzalutamide
Graphene quantum dot derivate
Castration-resistant prostate cancer
Online Access:http://link.springer.com/article/10.1186/s12951-020-00607-4

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http://link.springer.com/article/10.1186/s12951-020-00607-4

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