Inactivation of ackA and pta Genes Reduces GlpT Expression and Susceptibility to Fosfomycin in Escherichia coli

Inactivation of ackA and pta Genes Reduces GlpT Expression and Susceptibility to Fosfomycin in Escherichia coli

ABSTRACT Fosfomycin is used to treat a variety of bacterial infections, including urinary tract infections caused by Escherichia coli. In recent years, quinolone-resistant and extended-spectrum β-lactamase (ESBL)-producing bacteria have been increasing. Because fosfomycin is effective against many o...

Full description

Bibliographic Details
Main Authors: Hidetada Hirakawa, Ayako Takita, Yumika Sato, Suguru Hiramoto, Yusuke Hashimoto, Noriyasu Ohshima, Yoji A. Minamishima, Masami Murakami, Haruyoshi Tomita
Format: Article
Language:English
Published: American Society for Microbiology 2023-06-01
Series:Microbiology Spectrum
Subjects:
antimicrobial resistance
AMR
fosfomycin
urinary tract infection
UTI
bacterial pathogenesis
Online Access:https://journals.asm.org/doi/10.1128/spectrum.05069-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.05069-22

Similar Items