A systematic framework for molecular dynamics simulations of protein post-translational modifications.
By directly affecting structure, dynamics and interaction networks of their targets, post-translational modifications (PTMs) of proteins play a key role in different cellular processes ranging from enzymatic activation to regulation of signal transduction to cell-cycle control. Despite the great imp...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS Computational Biology |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23874192/?tool=EBI |