Clinical Trial Simulation To Optimize Trial Design for Fludarabine Dosing Strategies in Allogeneic Hematopoietic Cell Transplantation

Clinical Trial Simulation To Optimize Trial Design for Fludarabine Dosing Strategies in Allogeneic Hematopoietic Cell Transplantation

Optimal fludarabine exposure has been associated with improved treatment outcome in allogeneic hematopoietic cell transplantation, suggesting potential benefit of individualized dosing. A randomized controlled trial (RCT) comparing alternative fludarabine dosing strategies to current practice may be...

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Bibliographic Details
Main Authors: Jurgen B. Langenhorst, Thomas P.C. Dorlo, Charlotte vanKesteren, Erik M. vanMaarseveen, Stefan Nierkens, Moniek A. deWitte, Jaap Jan Boelens, Alwin D.R. Huitema
Format: Article
Language:English
Published: Wiley 2020-05-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.12486

Internet

https://doi.org/10.1002/psp4.12486

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