A Model-Based Framework to Identify Optimal Administration Protocols for Immunotherapies in Castration-Resistance Prostate Cancer

A Model-Based Framework to Identify Optimal Administration Protocols for Immunotherapies in Castration-Resistance Prostate Cancer

Prostate cancer (PCa) is one of the most frequent cancer in male population. Androgen deprivation therapy is the first-line strategy for the metastatic stage of the disease, but, inevitably, PCa develops resistance to castration (CRPC), becoming incurable. In recent years, clinical trials are testin...

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Bibliographic Details
Main Authors: Roberta Coletti, Andrea Pugliese, Andrea Lunardi, Orazio Caffo, Luca Marchetti
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
prostate cancer
immunotherapy
optimal administration protocols
ipilimumab
sipuleucel-T
mathematical modeling
Online Access:https://www.mdpi.com/2072-6694/14/1/135

Internet

https://www.mdpi.com/2072-6694/14/1/135

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