HOOK3 suppresses proliferation and metastasis in gastric cancer via the SP1/VEGFA axis

Abstract HOOK3, a member of the human hook microtubule-tethering protein family, has been implicated in the progression of cancer. However, the role of HOOK3 in the pathogenesis of gastric cancer (GC) remains incompletely understood. In this study, we investigated the expression of HOOK3 protein in...

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Bibliographic Details
Main Authors: Kexi Yang, Juntao Li, Jinghan Zhu, Yuqi Chen, Yuxin He, Jiayu Wang, Kanger Shen, Kun Wang, Tongguo Shi, Weichang Chen
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-01808-8