Programming Multifaceted Pulmonary T Cell Immunity by Combination Adjuvants

Programming Multifaceted Pulmonary T Cell Immunity by Combination Adjuvants

Summary: Induction of protective mucosal T cell memory remains a formidable challenge to vaccinologists. Using a combination adjuvant strategy that elicits potent CD8 and CD4 T cell responses, we define the tenets of vaccine-induced pulmonary T cell immunity. An acrylic-acid-based adjuvant (ADJ), in...

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Bibliographic Details
Main Authors: Chandranaik B. Marinaik, Brock Kingstad-Bakke, Woojong Lee, Masato Hatta, Michelle Sonsalla, Autumn Larsen, Brandon Neldner, David J. Gasper, Ross M. Kedl, Yoshihiro Kawaoka, M. Suresh
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Cell Reports Medicine
Subjects:
adjuvants
CD8
CD4
respiratory immunity
influenza virus
T1 and T17 programming
Online Access:http://www.sciencedirect.com/science/article/pii/S266637912030121X

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http://www.sciencedirect.com/science/article/pii/S266637912030121X

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