Mathematical model of a short translatable G-quadruplex and an assessment of its relevance to misfolding-induced proteostasis

G-quadruplexes can form in protein coding and non-coding segments such as the untranslated regions and introns of the mRNA transcript of several genes. This implies that amino acid forms of the G-quadruplex may have important consequences for protein homeostasis and the diseases caused by their alte...

Full description

Bibliographic Details
Main Author: Siddhartha Kundu
Format: Article
Language:English
Published: AIMS Press 2020-02-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2020135?viewType=HTML