Anthocyanins Activate Membrane Estrogen Receptors With Nanomolar Potencies to Elicit a Nongenomic Vascular Response Via NO Production

Anthocyanins Activate Membrane Estrogen Receptors With Nanomolar Potencies to Elicit a Nongenomic Vascular Response Via NO Production

Background The vascular pharmacodynamics of anthocyanins is only partially understood. To examine whether the anthocyanin‐induced vasorelaxation is related to membrane estrogen receptor activity, the role of ERα or GPER antagonism was ascertained on anthocyanins or 17‐β estradiol‐(E2) induced vasodi...

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Bibliographic Details
Main Authors: Camila Calfío, Francisca Donoso, J. Pablo Huidobro‐Toro
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
anthocyanins
endothelium
GPER and ERα
NO production
nongenomic steroidal actions
vasodilation
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.119.020498

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.119.020498

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