Regulation of the ER stress response by a mitochondrial microprotein

Regulation of the ER stress response by a mitochondrial microprotein

Cells trigger an unfolded protein response (UPR) in the endoplasmic reticulum, but its regulation by mitochondria is unclear. Here, the authors report a 54-residue microprotein PIGBOS that participates in inter-organelle contact between the endoplasmic reticulum and the mitochondria and may regulate...

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Bibliographic Details
Main Authors: Qian Chu, Thomas F. Martinez, Sammy Weiser Novak, Cynthia J. Donaldson, Dan Tan, Joan M. Vaughan, Tina Chang, Jolene K. Diedrich, Leo Andrade, Andrew Kim, Tong Zhang, Uri Manor, Alan Saghatelian
Format: Article
Language:English
Published: Nature Portfolio 2019-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12816-z

Internet

https://doi.org/10.1038/s41467-019-12816-z

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