Alteration of plasma glutamate and glutamine levels in children with high-functioning autism.

It has recently been hypothesized that hyperglutamatergia in the brain is involved in the pathophysiology of autism. However, there is no conclusive evidence of the validity of this hypothesis. As peripheral glutamate/glutamine levels have been reported to be correlated with those of the central ner...

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Bibliographic Details
Main Authors: Chie Shimmura, Shiro Suda, Kenji J Tsuchiya, Kenji Hashimoto, Koji Ohno, Hideo Matsuzaki, Keiko Iwata, Kaori Matsumoto, Tomoyasu Wakuda, Yosuke Kameno, Katsuaki Suzuki, Masatsugu Tsujii, Kazuhiko Nakamura, Nori Takei, Norio Mori
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3187770?pdf=render