Caffeic acid, but not ferulic acid, inhibits macrophage pyroptosis by directly blocking gasdermin D activation

Caffeic acid, but not ferulic acid, inhibits macrophage pyroptosis by directly blocking gasdermin D activation

Abstract Regulated pyroptosis is critical for pathogen elimination by inducing infected cell rupture and pro‐inflammatory cytokines secretion, while overwhelmed pyroptosis contributes to organ dysfunction and pathological inflammatory response. Caffeic acid (CA) and ferulic acid (FA) are both well‐k...

Full description

Bibliographic Details
Main Authors: Mingjiang Liu, Dandan Liu, Chenglong Yu, Hua hao Fan, Xin Zhao, Huiwen Wang, Chi Zhang, Minxia Zhang, Ruonan Bo, Shasha He, Xuerui Wang, Hui Jiang, Yuhong Guo, Jingui Li, Xiaolong Xu, Qingquan Liu
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:MedComm
Subjects:
caffeic acid
ferulic acid
gasdermin D
macrophage
pyroptosis
sepsis
Online Access:https://doi.org/10.1002/mco2.255

Internet

https://doi.org/10.1002/mco2.255

Similar Items