Synthesis and biological evaluation of [131I]iodocarvedilol as a potential radiopharmaceutical for heart imaging
Abstract The optimization of the radiolabeling yield of carvedilol with iodine-131 was described. Dependence of the labeling yield of [131I]iodocarvedilol on the concentration of carvedilol, chloramine-T content, pH of the reaction mixture and reaction time was studied in details. Carvedilol was lab...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-03-01
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Series: | BMC Chemistry |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13065-023-00935-0 |