Synthesis and biological evaluation of [131I]iodocarvedilol as a potential radiopharmaceutical for heart imaging

Abstract The optimization of the radiolabeling yield of carvedilol with iodine-131 was described. Dependence of the labeling yield of [131I]iodocarvedilol on the concentration of carvedilol, chloramine-T content, pH of the reaction mixture and reaction time was studied in details. Carvedilol was lab...

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Bibliographic Details
Main Authors: M. A. Motaleb, K M Attalah, H A Shweeta, I. T. Ibrahim
Format: Article
Language:English
Published: BMC 2023-03-01
Series:BMC Chemistry
Subjects:
Online Access:https://doi.org/10.1186/s13065-023-00935-0