Glycosylation network mapping and site-specific glycan maturation in vivo

Summary: Glycoprotein processing along a complex highly compartmentalized pathway is a hallmark of eukaryotic cells. We followed the kinetics of intracellular, site-specific glycan processing of a model protein with five distinct N-glycosylation sites and deduced a mathematical model of the secretor...

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Bibliographic Details
Main Authors: Marie-Estelle Losfeld, Ernesto Scibona, Chia-wei Lin, Markus Aebi
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222016893