Abundant and Diverse Clustered Regularly Interspaced Short Palindromic Repeat Spacers in <named-content content-type="genus-species">Clostridium difficile</named-content> Strains and Prophages Target Multiple Phage Types within This Pathogen

ABSTRACT Clostridium difficile is an important human-pathogenic bacterium causing antibiotic-associated nosocomial infections worldwide. Mobile genetic elements and bacteriophages have helped shape C. difficile genome evolution. In many bacteria, phage infection may be controlled by a form of bacter...

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Bibliographic Details
Main Authors: Katherine R. Hargreaves, Cesar O. Flores, Trevor D. Lawley, Martha R. J. Clokie
Format: Article
Language:English
Published: American Society for Microbiology 2014-10-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.01045-13