Astrocytes control hippocampal synaptic plasticity through the vesicular-dependent release of D-serine

Astrocytes control hippocampal synaptic plasticity through the vesicular-dependent release of D-serine

Astrocytes, the most abundant glial cells in the central nervous system (CNS), sense synaptic activity and respond through the release of gliotransmitters, a process mediated by intracellular Ca2+ level changes and SNARE-dependent mechanisms. Ionotropic N-methyl-D-aspartate (NMDA) receptors, which a...

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Bibliographic Details
Main Authors: Daniela Sofia Abreu, Joana I. Gomes, Filipa F. Ribeiro, Maria J. Diógenes, Ana M. Sebastião, Sandra H. Vaz
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
astrocyte
gliotransmission
d-serine
synaptic plasticity
tripartite synapse
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1282841/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2023.1282841/full

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