Tyr76 is essential for the cold adaptation of a class II glutaredoxin 4 with a heat‐labile structure from the Arctic bacterium Sphingomonas sp.

Tyr76 is essential for the cold adaptation of a class II glutaredoxin 4 with a heat‐labile structure from the Arctic bacterium Sphingomonas sp.

Glutaredoxins (Grxs) are small proteins that share a well‐conserved thioredoxin (Trx)‐fold and participate in many biological processes. This study examined the cold adaptation mechanism of a Fe‐S cluster binding class II Grx4 (SpGrx4) from the psychrophilic Arctic bacterium Sphingomonas sp. PAMC 26...

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Bibliographic Details
Main Authors: Trang Hoang, ChanSu Jeong, Sei‐Heon Jang, ChangWoo Lee
Format: Article
Language:English
Published: Wiley 2023-03-01
Series:FEBS Open Bio
Subjects:
aromatic amino acids
cis‐proline loop
cold adaptation
glutaredoxin
hydrogen bond network
thioredoxin‐fold
Online Access:https://doi.org/10.1002/2211-5463.13560

Internet

https://doi.org/10.1002/2211-5463.13560

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