(5<i>Z</i>,9<i>Z</i>)-14-[(3,28-Dioxoolean-12-en-28-yl)oxy]tetradeca-5,9-dienoic Acid with Cytotoxic Activity

(5<i>Z</i>,9<i>Z</i>)-14-[(3,28-Dioxoolean-12-en-28-yl)oxy]tetradeca-5,9-dienoic Acid with Cytotoxic Activity

For the first time, a synthetic analogue of natural (5Z,9Z)-dienoic acid has been synthesized in the form of a hybrid molecule containing a fragment of oleanolic acid and (5Z,9Z)-tetradeca-5.9-dienedicarboxylic acid, synthesized using a new reaction of Ti-catalyzed homo-cyclomagnesiation 1,2-dienes....

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Bibliographic Details
Main Authors: Regina A. Tuktarova, Lilya U. Dzhemileva, Usein M. Dzhemilev
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Molbank
Subjects:
hybrid molecules
oleanolic acid
(5<i>Z</i>,9<i>Z</i>)-dienoic acid
cytotoxic activity
apoptosis
cell cycle
Online Access:https://www.mdpi.com/1422-8599/2024/1/M1758

Internet

https://www.mdpi.com/1422-8599/2024/1/M1758

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