Decomposing heritability and genetic covariance by direct and indirect effect paths.

Estimation of heritability and genetic covariance is crucial for quantifying and understanding complex trait genetic architecture and is employed in almost all recent genome-wide association studies (GWAS). However, many existing approaches for heritability estimation and almost all methods for esti...

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Autors principals: Jie Song, Yiqing Zou, Yuchang Wu, Jiacheng Miao, Ze Yu, Jason M Fletcher, Qiongshi Lu
Format: Article
Idioma:English
Publicat: Public Library of Science (PLoS) 2023-01-01
Col·lecció:PLoS Genetics
Accés en línia:https://doi.org/10.1371/journal.pgen.1010620