Omega-3 fatty acid intake suppresses induction of diverse autoantibody repertoire by crystalline silica in lupus-prone mice

Inhalation of crystalline silica (cSiO2) in the workplace is etiologically linked to lupus and other autoimmune diseases. Exposing lupus-prone NZBWF1 mice to respirable cSiO2 unleashes a vicious cycle of inflammation and cell death in the lung that triggers interferon-regulated gene expression, ecto...

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Main Authors: Lichchavi D. Rajasinghe, Quan-Zhen Li, Chengsong Zhu, Mei Yan, Preeti S. Chauhan, Kathryn A. Wierenga, Melissa A. Bates, Jack R. Harkema, Abby D. Benninghoff, James J. Pestka
Format: Article
Language:English
Published: Taylor & Francis Group 2020-10-01
Series:Autoimmunity
Subjects:
Online Access:http://dx.doi.org/10.1080/08916934.2020.1801651