How epigenome drives chromatin folding and dynamics, insights from efficient coarse-grained models of chromosomes.
The 3D organization of chromosomes is crucial for regulating gene expression and cell function. Many experimental and polymer modeling efforts are dedicated to deciphering the mechanistic principles behind chromosome folding. Chromosomes are long and densely packed-topologically constrained-polymers...
| Main Authors: | , |
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| 格式: | 文件 |
| 语言: | English |
| 出版: |
Public Library of Science (PLoS)
2018-05-01
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| 丛编: | PLoS Computational Biology |
| 在线阅读: | https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1006159&type=printable |