WNK1 promotes water homeostasis by acting as a central osmolality sensor for arginine vasopressin release
Maintaining internal osmolality constancy is essential for life. Release of arginine vasopressin (AVP) in response to hyperosmolality is critical. Current hypotheses for osmolality sensors in circumventricular organs (CVOs) of the brain focus on mechanosensitive membrane proteins. The present study...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Clinical Investigation
2023-06-01
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Series: | The Journal of Clinical Investigation |
Subjects: | |
Online Access: | https://doi.org/10.1172/JCI164222 |