In Vitro Activities of Ceftazidime–Avibactam and Aztreonam–Avibactam at Different Inoculum Sizes of Extended-Spectrum β-Lactam-Resistant Enterobacterales Blood Isolates

In Vitro Activities of Ceftazidime–Avibactam and Aztreonam–Avibactam at Different Inoculum Sizes of Extended-Spectrum β-Lactam-Resistant Enterobacterales Blood Isolates

β-lactam–avibactam combinations have been proposed as carbapenem-sparing therapies, but little data exist on their in vitro activities in infections with high bacterial inocula. We investigated the in vitro efficacies and the inoculum effects of ceftazidime–avibactam and aztreonam–avibactam against...

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Bibliographic Details
Main Authors: Moonsuk Bae, Taeeun Kim, Joung Ha Park, Seongman Bae, Heungsup Sung, Mi-Na Kim, Jiwon Jung, Min Jae Kim, Sung-Han Kim, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Yong Pil Chong
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Antibiotics
Subjects:
inoculum effect
ceftazidime–avibactam
aztreonam-avibactam
extended-spectrum β-lactam-resistant enterobacterales
Online Access:https://www.mdpi.com/2079-6382/10/12/1492

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https://www.mdpi.com/2079-6382/10/12/1492

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