In TFIIH, XPD helicase is exclusively devoted to DNA repair.

In TFIIH, XPD helicase is exclusively devoted to DNA repair.

The eukaryotic XPD helicase is an essential subunit of TFIIH involved in both transcription and nucleotide excision repair (NER). Mutations in human XPD are associated with several inherited diseases such as xeroderma pigmentosum, Cockayne syndrome, and trichothiodystrophy. We performed a comparativ...

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Bibliographic Details
Main Authors: Jochen Kuper, Cathy Braun, Agnes Elias, Gudrun Michels, Florian Sauer, Dominik R Schmitt, Arnaud Poterszman, Jean-Marc Egly, Caroline Kisker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-09-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.1001954

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https://doi.org/10.1371/journal.pbio.1001954

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