Three-Dimensional Geometry of Collagenous Tissues by Second Harmonic Polarimetry

Abstract Collagen is a biological macromolecule capable of second harmonic generation, allowing label-free detection in tissues; in addition, molecular orientation can be determined from the polarization dependence of the second harmonic signal. Previously we reported that in-plane orientation of co...

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Bibliographic Details
Main Authors: Karen Reiser, Patrick Stoller, André Knoesen
Format: Article
Language:English
Published: Nature Portfolio 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02326-7