Rap1 in the VMH regulates glucose homeostasis

Rap1 in the VMH regulates glucose homeostasis

The hypothalamus is a critical regulator of glucose metabolism and is capable of correcting diabetes conditions independently of an effect on energy balance. The small GTPase Rap1 in the forebrain is implicated in high-fat diet–induced (HFD-induced) obesity and glucose imbalance. Here, we report tha...

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Bibliographic Details
Main Authors: Kentaro Kaneko, Hsiao-Yun Lin, Yukiko Fu, Pradip K. Saha, Ana B. De la Puente-Gomez, Yong Xu, Kousaku Ohinata, Peter Chen, Alexei Morozov, Makoto Fukuda
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-06-01
Series:JCI Insight
Subjects:
Metabolism
Neuroscience
Online Access:https://doi.org/10.1172/jci.insight.142545

Internet

https://doi.org/10.1172/jci.insight.142545

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