Deterministic mechanical model of T-killer cell polarization reproduces the wandering of aim between simultaneously engaged targets.

T-killer cells of the immune system eliminate virus-infected and tumorous cells through direct cell-cell interactions. Reorientation of the killing apparatus inside the T cell to the T-cell interface with the target cell ensures specificity of the immune response. The killing apparatus can also osci...

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Bibliographic Details
Main Authors: Mun Ju Kim, Ivan V Maly
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19132078/?tool=EBI