Characterization of a pleiotropic regulator MtrA in Streptomyces avermitilis controlling avermectin production and morphological differentiation

Characterization of a pleiotropic regulator MtrA in Streptomyces avermitilis controlling avermectin production and morphological differentiation

Abstract Background The macrolide antibiotic avermectin, a natural product derived from Streptomyces avermitilis, finds extensive applications in agriculture, animal husbandry and medicine. The mtrA (sav_5063) gene functions as a transcriptional regulator belonging to the OmpR family. As a pleiotrop...

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Bibliographic Details
Main Authors: Jinpin Tian, Yue Li, Chuanbo Zhang, Jianyu Su, Wenyu Lu
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Microbial Cell Factories
Subjects:
MtrA
Avermectin
S. avermitilis
Transcriptional regulators
Secondary metabolism
Online Access:https://doi.org/10.1186/s12934-024-02331-2

Internet

https://doi.org/10.1186/s12934-024-02331-2

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