QTL mapping of natural variation reveals that the developmental regulator bruno reduces tolerance to P-element transposition in the Drosophila female germline.

QTL mapping of natural variation reveals that the developmental regulator bruno reduces tolerance to P-element transposition in the Drosophila female germline.

Transposable elements (TEs) are obligate genetic parasites that propagate in host genomes by replicating in germline nuclei, thereby ensuring transmission to offspring. This selfish replication not only produces deleterious mutations-in extreme cases, TE mobilization induces genotoxic stress that pr...

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Bibliographic Details
Main Authors: Erin S Kelleher, Jaweria Jaweria, Uchechukwu Akoma, Lily Ortega, Wenpei Tang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-10-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC6207299?pdf=render

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http://europepmc.org/articles/PMC6207299?pdf=render

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