Enhanced ROCK1 dependent contractility in fibroblast from chronic obstructive pulmonary disease patients

Enhanced ROCK1 dependent contractility in fibroblast from chronic obstructive pulmonary disease patients

<p>Abstract</p> <p>Background</p> <p>During wound healing processes fibroblasts account for wound closure by adopting a contractile phenotype. One disease manifestation of COPD is emphysema which is characterized by destruction of alveolar walls and our hypothesis is th...

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Bibliographic Details
Main Authors: Hallgren Oskar, Rolandsson Sara, Andersson-Sjöland Annika, Nihlberg Kristian, Wieslander Elisabet, Kvist-Reimer Martina, Dahlbäck Magnus, Eriksson Leif, Bjermer Leif, Erjefält Jonas S, Löfdahl Claes-Göran, Westergren-Thorsson Gunilla
Format: Article
Language:English
Published: BMC 2012-08-01
Series:Journal of Translational Medicine
Subjects:
Chronic obstructive pulmonary disease
Contractility
Emphysema
Fibroblast/myofibroblast
Rho-associated coiled-coil protein kinase 1
Online Access:http://www.translational-medicine.com/content/10/1/171

Internet

http://www.translational-medicine.com/content/10/1/171

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