Enhanced ROCK1 dependent contractility in fibroblast from chronic obstructive pulmonary disease patients

Enhanced ROCK1 dependent contractility in fibroblast from chronic obstructive pulmonary disease patients

<p>Abstract</p> <p>Background</p> <p>During wound healing processes fibroblasts account for wound closure by adopting a contractile phenotype. One disease manifestation of COPD is emphysema which is characterized by destruction of alveolar walls and our hypothesis is th...

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Bibliographic Details
Main Authors:	Hallgren Oskar, Rolandsson Sara, Andersson-Sjöland Annika, Nihlberg Kristian, Wieslander Elisabet, Kvist-Reimer Martina, Dahlbäck Magnus, Eriksson Leif, Bjermer Leif, Erjefält Jonas S, Löfdahl Claes-Göran, Westergren-Thorsson Gunilla
Format:	Article
Language:	English
Published:	BMC 2012-08-01
Series:	Journal of Translational Medicine
Subjects:	Chronic obstructive pulmonary disease Contractility Emphysema Fibroblast/myofibroblast Rho-associated coiled-coil protein kinase 1
Online Access:	http://www.translational-medicine.com/content/10/1/171

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