Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM

Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM

The β-barrel assembly machinery (BAM complex) is a key mediator of outer membrane protein biogenesis in Gram-negative bacteria. Here the authors report a cryo-EM structure of the intact BAM complex that suggests that lateral gate opening is a necessary part of the BAM functional cycle.

Bibliographic Details
Main Authors: Matthew G. Iadanza, Anna J. Higgins, Bob Schiffrin, Antonio N. Calabrese, David J. Brockwell, Alison E. Ashcroft, Sheena E. Radford, Neil A. Ranson
Format: Article
Language:English
Published: Nature Portfolio 2016-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12865

Internet

https://doi.org/10.1038/ncomms12865

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