Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM
The β-barrel assembly machinery (BAM complex) is a key mediator of outer membrane protein biogenesis in Gram-negative bacteria. Here the authors report a cryo-EM structure of the intact BAM complex that suggests that lateral gate opening is a necessary part of the BAM functional cycle.
Main Authors: | Matthew G. Iadanza, Anna J. Higgins, Bob Schiffrin, Antonio N. Calabrese, David J. Brockwell, Alison E. Ashcroft, Sheena E. Radford, Neil A. Ranson |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2016-09-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms12865 |
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