CD163 protein inhibits lipopolysaccharide-induced macrophage transformation from M2 to M1 involved in disruption of the TWEAK–Fn14 interaction

CD163 protein inhibits lipopolysaccharide-induced macrophage transformation from M2 to M1 involved in disruption of the TWEAK–Fn14 interaction

Macrophages play a crucial role in regulating inflammation and innate immune responses, and their polarization into distinct phenotypes, such as M1 and M2, is involved in various diseases. However, the specific role of CD163, a scavenger receptor expressed by macrophages, in the transformation of M2...

Full description

Bibliographic Details
Main Authors: Linjian Chen, Wanchun Mei, Juan Song, Kuncheng Chen, Wei Ni, Lin Wang, Zhaokai Li, Xiaofeng Ge, Liuhang Su, Chenlu Jiang, Binbin Liu, Cuilian Dai
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Heliyon
Subjects:
CD163
Macrophage polarization
TWEAK
Fn14
NF-κB
M1
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023104312

Internet

http://www.sciencedirect.com/science/article/pii/S2405844023104312

Similar Items