A low-carbohydrate diet induces hepatic insulin resistance and metabolic associated fatty liver disease in mice

A low-carbohydrate diet induces hepatic insulin resistance and metabolic associated fatty liver disease in mice

Objectives: Metabolic-associated fatty liver disease (MAFLD) is the most common chronic liver disease that can range from hepatic steatosis to non-alcoholic steatohepatitis (NASH), which can lead to fibrosis and cirrhosis. Recently, ketogenic diet (KD), a low carbohydrate diet, gained popularity as...

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Bibliographic Details
Main Authors: Fen Long, Memoona R. Bhatti, Alexandra Kellenberger, Wenfei Sun, Salvatore Modica, Marcus Höring, Gerhard Liebisch, Jean-Philippe Krieger, Christian Wolfrum, Tenagne D. Challa
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Molecular Metabolism
Subjects:
Ketogenic diet
Hepatic insulin resistance
NASH
MAFLD
IL6
JNK
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877823000091

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http://www.sciencedirect.com/science/article/pii/S2212877823000091

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