Narrative review of the influence of diabetes mellitus and hyperglycemia on colorectal cancer risk and oncological outcomes

Diabetes mellitus (DM) and hyperglycemia have been shown to have significant effects on the incidence, chemoresistance, and prognosis of colorectal cancer (CRC), as well as the outcomes of localized and metastatic CRC. Inflammation and endocrine effects may act as central mechanisms of DM and cancer...

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Bibliographic Details
Main Authors: Hsiu-Chung Cheng, Tsung-Kun Chang, Wei-Chih Su, Hsiang-Lin Tsai, Jaw-Yuan Wang
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Translational Oncology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523321000814