EphB4 Regulates Self-Renewal, Proliferation and Neuronal Differentiation of Human Embryonic Neural Stem Cells in Vitro

EphB4 Regulates Self-Renewal, Proliferation and Neuronal Differentiation of Human Embryonic Neural Stem Cells in Vitro

Background/Aims: EphB4 belongs to the largest family of Eph receptor tyrosine kinases. It contributes to a variety of pathological progresses of cancer malignancy. However, little is known about its role in neural stem cells (NSCs). This study examined whether EphB4 is required for proliferation and...

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Bibliographic Details
Main Authors: Tingting Liu, Xianwei Zeng, Fangling Sun, Hongli Hou, Yunqian Guan, Deyu Guo, Houxi Ai, Wen Wang, Guojun Zhang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
EphB4 signaling
Neural stem cells
Self-renewal
Proliferation
Differentiation
Neuron
Online Access:http://www.karger.com/Article/FullText/459693

Internet

http://www.karger.com/Article/FullText/459693

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