Identification of a Locus in Mice that Regulates the Collateral Damage and Lethality of Virus Infection

Identification of a Locus in Mice that Regulates the Collateral Damage and Lethality of Virus Infection

Summary: Arenaviruses can cause severe hemorrhagic disease in humans, which can progress to organ failure and death. The underlying mechanisms causing lethality and person-to-person variation in outcome remain incompletely explained. Herein, we characterize a mouse model that recapitulates many feat...

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Main Authors: Ichiro Misumi, Kevin D. Cook, Joseph E. Mitchell, Makayla M. Lund, Sarah C. Vick, Robert H. Lee, Toru Uchimura, Wolfgang Bergmeier, Piotr Mieczkowski, Fernando Pardo-Manuel de Villena, Jenny P.Y. Ting, Jason K. Whitmire
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719304590

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http://www.sciencedirect.com/science/article/pii/S2211124719304590

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