Inhibition of Dot1L Alleviates Fulminant Hepatitis Through Myeloid-Derived Suppressor CellsSummary

Inhibition of Dot1L Alleviates Fulminant Hepatitis Through Myeloid-Derived Suppressor CellsSummary

Background & Aims: Fulminant hepatitis (FH) is a clinical syndrome characterized by sudden and severe liver dysfunction. Dot1L, a histone methyltransferase, is implicated in various physiologic and pathologic processes, including transcription regulation and leukemia. However, the role of Do...

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Bibliographic Details
Main Authors: Wanlin Yang, Hongshuang Yu, Jiefang Huang, Xiang Miao, Qiwei Wang, Yanan Wang, Yiji Cheng, Shan He, Fang Zhao, Lijun Meng, Bei Wang, Fengtao Qian, Xiaohui Ren, Min Jin, Yuting Gu, Yanyun Zhang, Wei Cai
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Fulminant Hepatitis
Histone Methyltransferase Dot1L
Inducible Nitric Oxide Synthase
Myeloid-Derived Suppressor Cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X21000199

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http://www.sciencedirect.com/science/article/pii/S2352345X21000199

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