Ability of human SNAP-23 to generate high molecular weight SDS-resistant ternary SNARE complexes is influenced by C-terminal coil content

Ability of human SNAP-23 to generate high molecular weight SDS-resistant ternary SNARE complexes is influenced by C-terminal coil content

Using in vitro protein complex formation assay, ability of SNAP-25 isoforms to generate SDS-resistant ternary SNARE complexes with Syntaxin-1 and VAMP-2 was investigated. Major SNAP-25 family proteins were found to generate heat-resistant ternary complexes with varying efficiency. Compared to human...

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Bibliographic Details
Main Authors: Vadakkanchery V. Vaidyanathan, Thomas Binz
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
SNAP-25 and SNAP-23 proteins
SDS-Resistant ternary SNARE complexes
C-terminal coiled-coil content
Botulinum neurotoxin cleavage
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580821002442

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http://www.sciencedirect.com/science/article/pii/S2405580821002442

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