Multimodal CEA-targeted fluorescence and radioguided cytoreductive surgery for peritoneal metastases of colorectal origin

Imaging of tumor burden during surgery can lead to better tumor resection. Here, the authors develop a fluorescent probe that binds to carcinoembryonic antigen, expressed on colorectal cancer cells, and describe the results of their phase I clinical trial.

Bibliographic Details
Main Authors: Jan Marie de Gooyer, Fortuné M. K. Elekonawo, Andreas J. A. Bremers, Otto C. Boerman, Erik H. J. G. Aarntzen, Philip R. de Reuver, Iris. D. Nagtegaal, Mark Rijpkema, Johannes H. W. de Wilt
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-29630-9