RNA editing enzyme ADAR1 is required for early T cell development
Abstract. The RNA editing enzyme ADAR1 has been shown to be an essential molecule for hematopoietic cell differentiation, embryonic development, and regulation of immune responses. Here, we present evidence in a T-cell-specific gene knockout mouse model that ADAR1 is required for early T cell develo...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Health
2020-01-01
|
Series: | Blood Science |
Online Access: | http://journals.lww.com/10.1097/BS9.0000000000000039 |