Ultrasensitivity of microtubule severing due to damage repair

Summary: Microtubule-based cytoskeletal structures aid in cell motility, cell polarization, and intracellular transport. These functions require a coordinated effort of regulatory proteins which interact with microtubule cytoskeleton distinctively. In-vitro experiments have shown that free tubulin c...

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Bibliographic Details
Main Authors: Chloe E. Shiff, Jane Kondev, Lishibanya Mohapatra
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224000956