Lack of p53 function promotes radiation-induced mitotic catastrophe in mouse embryonic fibroblast cells
<p>Abstract</p> <p>Background</p> <p>We have demonstrated that in some human cancer cells both chronic mild heat and ionizing radiation exposures induce a transient block in S and G2 phases of the cell cycle. During this delay, cyclin B1 protein accumulates to supranorm...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2006-04-01
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Series: | Cancer Cell International |
Online Access: | http://www.cancerci.com/content/6/1/11 |