Mitochondrial inorganic polyphosphate is required to maintain proteostasis within the organelle

Mitochondrial inorganic polyphosphate is required to maintain proteostasis within the organelle

The existing literature points towards the presence of robust mitochondrial mechanisms aimed at mitigating protein dyshomeostasis within the organelle. However, the precise molecular composition of these mechanisms remains unclear. Our data show that inorganic polyphosphate (polyP), a polymer well-c...

Full description

Bibliographic Details
Main Authors: Renata T. Da Costa, Pedro Urquiza, Matheus M. Perez, YunGuang Du, Mei Li Khong, Haiyan Zheng, Mariona Guitart-Mampel, Pia A. Elustondo, Ernest R. Scoma, Vedangi Hambardikar, Beatrix Ueberheide, Julian A. Tanner, Alejandro Cohen, Evgeny V. Pavlov, Cole M. Haynes, Maria E. Solesio
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
mitochondria
mitochondrial inorganic polyphosphate
polyP
protein homeostasis
proteostasis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1423208/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2024.1423208/full

Similar Items