Long-term progression of clinician-reported and gait performance outcomes in hereditary spastic paraplegias

Long-term progression of clinician-reported and gait performance outcomes in hereditary spastic paraplegias

IntroductionHereditary spastic paraplegias (HSPs) are a heterogeneous group of neurodegenerative diseases in which little is known about the most appropriate clinical outcome assessments (COAs) to capture disease progression. The objective of this study was to prospectively determine disease progres...

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Bibliographic Details
Main Authors: Diana Maria Cubillos Arcila, Gustavo Dariva Machado, Valéria Feijó Martins, Vanessa Bielefeldt Leotti, Rebecca Schüle, Leonardo Alexandre Peyré-Tartaruga, Jonas Alex Morales Saute
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Neuroscience
Subjects:
hereditary spastic paraplegias
gait analysis
clinical outcome assessment
performance outcomes
clinician-reported outcomes
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1226479/full

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https://www.frontiersin.org/articles/10.3389/fnins.2023.1226479/full

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