Reconsideration of the current models of estimated kidney function‐based drug dose adjustment in older adults: The role of biological age

Abstract Human lifespan has increased from a median of 46.5 years in 1950 to 71.7 years in 2022. As people age, one of the inevitable consequences is a decline in kidney function and glomerular filtration rate (GFR) which can have direct or indirect effects on the pharmacokinetic and pharmacodynamic...

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Bibliographic Details
Main Authors: Radin Alikhani, Manjunath P. Pai
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.13643