Increased Pro-Thrombotic Platelet Activity Associated with Thrombin/PAR1-Dependent Pathway Disorder in Patients with Secondary Progressive Multiple Sclerosis

Increased Pro-Thrombotic Platelet Activity Associated with Thrombin/PAR1-Dependent Pathway Disorder in Patients with Secondary Progressive Multiple Sclerosis

Epidemiological studies confirm the high risk of ischemic events in multiple sclerosis (MS) that are associated with increased pro-thrombotic activity of blood platelets. The most potent physiological platelet agonist is thrombin, which activates platelets via cleavage of specific protease-activated...

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Bibliographic Details
Main Authors: Angela Dziedzic, Elzbieta Miller, Michal Bijak, Lukasz Przyslo, Joanna Saluk-Bijak
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
thromboembolic consequences in multiple sclerosis
protease-activated receptors
blood platelets
megakaryocytes
Online Access:https://www.mdpi.com/1422-0067/21/20/7722

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https://www.mdpi.com/1422-0067/21/20/7722

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